10+ Heart-Healthy, Anti-Inflammatory Casserole Dinner Recipes

Creamy Chicken, Mushroom & Spinach Skillet Casserole

This spinach-packed casserole cooks on the stovetop and bakes in the same skillet for a family-friendly dinner with an easy cleanup. You can use leftover chicken and cook the pasta ahead of time to speed up the prep.

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Eggplant Tortilla Casserole

This layered casserole is inspired by classic cheese enchiladas, minus the fuss of rolling and stuffing individual tortillas. You'd never guess that within this comforting casserole hides a layer of thinly sliced eggplant. The thin slices become tender when roasted and add a subtle savory note.

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Green Chile Rotisserie Chicken Casserole

This green chile rotisserie chicken casserole features tender rotisserie chicken with lots of tender vegetables. The corn adds a nice pop of sweetness, while the rice helps absorb some of the flavors. A crunchy topping of crushed tortilla chips finishes off this comforting, Southwestern-inspired casserole.

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Teriyaki Chicken Skillet Casserole with Broccol

a recipe photo of the Teriyaki Chicken Casserole with Broccoli — Photographer: Brie Goldman, Food Stylist: Lauren McAnelly, Prop Stylist: Gabriel Greco

Whip up this quick and easy teriyaki chicken casserole in just one skillet—it’s the perfect go-to recipe for hectic weeknights that’s sure to satisfy a crowd. It’s ideal for making use of any leftover chicken and rice you have on hand. If you’re short on leftovers, a rotisserie chicken paired with a package of microwaveable brown rice is a good substitute.

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Chicken Tetrazzini

This retro dish will please kids and adults alike.

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Turkey-Vegetable Bake

Need to use up leftover turkey from the holidays? Make this low fat casserole. It's made with brown rice and lots of vegetables.

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Creamy Chicken & Penne alla Vodka Casserole with Peas

This cheesy chicken pasta casserole is perfect for a busy weeknight when you need a fast and easy dinner with minimal cleanup. Vodka sauce adds a creamy note to the sauce. If you don’t have vodka sauce on hand, add a few tablespoons of cream to regular marinara.

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Mom's Creamy Chicken & Broccoli Casserole

Mom's Creamy Chicken and Broccoli Casserole — Brian Woodcock; Styling: Cindy Barr

This lightened-up creamy chicken casserole is packed with veggies. The sauce at the heart of this family-friendly casserole uses fat-free milk with a combination of fat-free Greek-style yogurt and a little mayonnaise to give it body.

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Chicken-Spaghetti Squash Bake

In this version of a chicken-and-broccoli casserole, spaghetti squash takes on a creamy texture when baked with cream of mushroom soup.

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Smoked Turkey, Kale & Rice Bake

This hearty one-skillet dinner is loaded with celery, kale, tomatoes and quick-cooking brown rice. It's easy to make the recipe vegetarian by substituting smoked tofu for the turkey.

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Garlic Cashew Chicken Casserole

Combine brown rice, cashews, chow-mein noodles and vegetables galore with chicken in this delicious casserole.

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Florentine Lasagna Roll-Ups

Think portion control with these individual lasagna roll-ups. Leftovers are great for lunch the next day.

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Turkey & Leek Shepherd's Pie

The mashed potato-covered shepherd's pie was originally created to use up the leftovers from a festive roast. This version blends peas, leeks and carrots with diced turkey, all in a creamy herb sauce. The dish is a perfect way to create a second meal with the holiday turkey but if you like, use leftover roast chicken, duck or goose.

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